Pharmacological action Desonide Ointment
Synthetic corticosteroids. It possesses anti-inflammatory, antiallergic and antipruritic activity. Because the molecule Desonide Ointment no halogens, its antiproliferative effect on keratinocytes and fibroblasts expressed slightly, which reduces the likelihood thinning and atrophy of the tissue at the site of application.
Glucocorticoid for topical use in ophthalmology. In the molecule of the active substance is not halogen, which eliminates the possibility of negative effects on the epithelium and the subcutaneous tissue. The solubility of a substance in water eliminates foreign body sensation in the eye. When applied topically has anti-inflammatory effect: it reduces vascular permeability, chemotaxis, contributes to the stabilization of lysosomes, has a vasoconstrictor effect in inflammatory hyperemia.
Desonide Ointment Indications
For external use: allergic dermatitis, seborrhea, and various forms of eczema, atopic dermatitis, psoriasis, prurigo, red flat warty lichen. For topical application: inflammatory anterior segment and its appendages, allergic conjunctivitis, blepharitis scaly, episcleritis, recurrent iritis, iridocyclitis posterior segment eye, thermal and chemical destruction of the cornea.
Inflammatory diseases of the anterior segment and its appendages: allergic conjunctivitis, blepharitis scaly, episcleritis, recurrent iritis, iridocyclitis posterior segment eye; post-operative and post-traumatic inflammation, thermal and chemical destruction of the cornea.
The use of Desonide Ointment
Desonide administered in the form of eye drops (1-2 drops), or as an eye ointment 3 – 4 p / day. Perhaps the use of eye drops during the day and at night – the ointment. Treatment course – 12-15 days. Continuous use of the drug over a month is not recommended. Before starting treatment, make sure there are no contraindications. Prenatsid can be given for viral diseases caused by Herpes simplex, only in cases where both chemotherapy drugs for the treatment of herpes. It should be borne in mind that the application for the treatment of keratitis Desonide caused by Herpes simplex, requires great care and is valid only under the direct supervision of an ophthalmologist. In diseases causing thinning of the cornea, the use of Desonide could cause a perforation. Do not show drug use in injuries and abrasions of the cornea. During pregnancy and lactation, as well as children at an early age Desonide administered only if absolutely necessary and under strict medical supervision. It should be borne in mind that prolonged use can cause the development of Desonide glaucoma, angle and decrease in visual acuity, optic nerve damage, cataracts, perforation of the eyeball, the development of fungal infection. In long-term therapeutic use of drugs is often necessary to study the IOP. During treatment, handling and working with machines are not contraindicated.
Dosage and Desonide Ointment
Individual, depending on the indications and dosage form used.
Side effects Desonide Ointment
On the part of the vision: long-term use in ophthalmic practice may increase the intraocular pressure decrease in the angle of view, blurred vision, cataract, optic nerve damage, perforation of the eyeball.
Local reactions: tingling and burning sensations at the site of application.
Contra Desonide Ointment
Hypersensitivity to Desonide.
For local use: increased intraocular pressure, acute viral disease of the cornea (including caused by Herpes simplex) in the stage of ulceration, conjunctivitis with ulcerative keratitis, tuberculosis, eye, fungal eye, purulent ophthalmia, purulent conjunctivitis, purulent blepharitis, stye.
For external use: bacterial, viral, fungal skin diseases, tuberculosis, skin, syphilitic skin manifestations, skin tumors.
Pregnancy and breastfeeding
During pregnancy and lactation, as well as young children use strict indications and under medical supervision.
Cautions
Not recommended for use in injuries and abrasions of the cornea. When applied to large areas of skin or damaged skin, as well as in the case of occlusive dressings may increase the absorption and the manifestation of resorptive action. In diseases causing thinning of the cornea, the application may cause perforation of Desonide cornea.
